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The reason we have often been taught to avoid iv iron in patients with active infection is because iron serves as a growth factor for microorganisms and in theory may promote their growth and worsen the infection. However, real world data to support this is limited, and this article shows that when patients with active infection (even MRSA bacteremia) and iron deficiency anemia were treated with IV iron, survival actually trended up, not down. It is a retrospective study with obvious confounding
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