Background Acute upper gastrointestinal bleeding (AUGIB) is a common medical emergency with evolving demographics and ...

IBD has become a global disease in the 21st century that shifts through four epidemiological stages. Alterations in the gut ...

Background Eosinophilic oesophagitis (EoE) is a chronic allergic disease characterised by oesophageal epithelial remodelling, barrier dysfunction and inflammation. The transcription factor forkhead ...

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disorder worldwide, reflecting the growing prevalence of obesity and type 2 diabetes. Some patients ...

1 Department of Upper Gastro-intestinal Surgery, Hope Hospital, Salford Royal Hospitals NHS Trust, Manchester, UK 2 Department of Pathology, Hope Hospital, Salford Royal Hospitals NHS Trust, ...

Section of Cancer Genetics, Institute of Cancer Research, Sutton, UK Dr A Walther, Molecular and Population Genetics, London Research Institute, Cancer Research UK, 44 Lincoln’s Inn Fields, London ...

2 Inserm U954, Genetic Nutrition and Exposure to Environmental Risks (NGERE), University of Lorraine, Vandoeuvre- lès-Nancy, France Correspondence to Professor Laurent Peyrin-Biroulet, Inserm U954 and ...

1 Histopathology Unit, Cancer Research UK, Lincoln’s Inn Fields, London, UK 2 Histopathology Unit, Cancer Research UK, Lincoln’s Inn Fields, London, UK and Molecular Pathology Centre, Institute of ...

Objective Our previous studies have identified CXCL8 as the crucial chemokine responsible for gastric cancer metastasis mediated by loss of RACK1. However, the regulatory effect of CXCL8 on immune ...

15 Department of Gastroenterology and Hepatology, Singapore General Hospital, Singapore Background Metabolic dysfunction-associated steatotic liver disease (MASLD) affects over 30% of the general ...

Zhou and colleagues published an observational study on the beneficial effects of statin use in steatotic liver disease.1 Using a large, multicentre database, the author reported that statin use in ...

Faecal microbiota transplantation (FMT) has emerged as a transformative therapy for Clostridioides difficile infections and shows promise for various GI and systemic diseases. However, the poor ...