The authors proposed two hypotheses: first, that methamphetamine induces neuroinflammation, and second, that it alters neuronal stem cell differentiation. These are valuable hypotheses, and the ...

CRISPR construct to genetically ablate the GABA transporter GAT3 in the mouse visual cortex, with effects on population-level neuronal activity. This work is important, as it sheds light on how GAT3 ...

Characterization of intracellular synapse heterogeneity aides to understand the intricate computational logic of neuronal circuits. Despite recent advances in connectomics, the spatial patterns of ...

The Drosophila microbiome regulates the cycling of gut metabolites in a circadian clock and diet-dependent manner.

This important study introduces a Bayesian method to determine bacterial counts that accounts for the experimental noise inherent to dilution and plating methods, and distinguishes it from biological ...

Foveal sensitivity to the features of an imminent saccade target increases with the target’s conspicuity, supporting foveal prediction as a viable mechanism for maintaining visual continuity in ...

This important study presents a new method for longitudinally tracking cells in two-photon imaging data that addresses the specific challenges of imaging neurons in the developing cortex. It provides ...

Here, we address this question further by combining large-scale electrophysiological recordings, to characterize the functional connectivity of developing neuronal networks in vitro, with a generative ...

Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

Platelet-derived growth factors can restore the proliferative potential of senescent cells taken from the degenerated intervertebral discs of aged humans.

The chirality of tissues and organs is essential for their proper function and development. Tissue-level chirality derives from the chirality of individual cells that comprise the tissue, and cellular ...

Quantitative measurements of intra-Golgi transport kinetics of diverse secretory cargos challenge the classic cisternal progression model and support the stable compartment model of the Golgi.