Seahawks quarterback Geno Smith delivered in one of the season’s biggest moments and boosted Seattle to a much-needed victory over the rival San Francisco 49ers.

San Francisco 49ers running back Christian McCaffrey played his second game of the season on Sunday after a prolonged battle with Achilles tendinitis.

The San Francisco 49ers got a taste of what their defense looks like without Nick Bosa in the second half of a loss to ...

The AFC had a major shake-up after the thrilling Week 11 slate, even if not much changed in the standings. The Kansas City ...

The injury-prone San Francisco 49ers are monitoring yet another health issue, this one involving quarterback Brock Purdy's ...

Here are the top trolls from Week 11. The Indianapolis Colts came back to defeat the New York Jets 28-27 at MetLife Stadium.

If it wasn't clear before the Week 11 loss to the Seattle Seahawks, it is definitely clear now. The San Francisco 49ers are hungover from their Super Bowl loss ...

NFL Week 12 picks, predictions for scores for games this week, including Steelers vs Browns, Vikings vs Bears, Lions vs Colts ...

Meanwhile, Harbaugh is in Los Angeles, coaching the Chargers to a 7-3 record, with quarterback Justin Herbert looking like a superstar. And the reigning college national champion is bringing the quirk ...

Russell Wilson compared the Pittsburgh Steelers to his Super Bowl-winning Seattle Seahawks team after their win against the ...