The San Francisco 49ers still have a chance to claim the one seed in the NFC playoff bracket with a win in Week 16 over the Indianapolis Colts.

Buffalo, which is the No. 6 seed in the AFC playoff picture, is nearly a lock to make the postseason and have a clear path to pluck the AFC East title. The Bills trail the Patriots by one game with three games to play.

The 2025 NFL season has officially reached its home stretch. As we ready for this weekend, only five full weeks of regular-season action remain until the start of the playoffs. The postseason picture is far from finalized,

The Patriots squandered a commanding 21-0 lead against the Bills, ultimately losing 35-31 in a stunning Week 15 collapse. This defeat significantly im

Despite the gap, the Bills' AFC East title hopes are alive. The path is narrow and hinges on Buffalo winning in Foxborough in two weeks. Buffalo must win at New England on Dec. 14 to keeps its division championship hopes alive — and would still need to keep winning while the Patriots lose at least once more.

The New England Patriots area headed back to the postseason. With a 28-24 comeback win over the Baltimore Ravens on Sunday Night Football, the Patriots clinched a playoff berth in the first season under head coach Mike Vrabel.