The Jacksonville Jaguars have a key Week 12 matchup, with their road contest against the Arizona Cardinals having the potential to be the

Everything you need to know about the NFL match between Arizona Cardinals and Jacksonville Jaguars, as well as kick-off time and team news

Veteran quarterback Jacoby Brissett’s 10-year NFL career has included several twists and turns. He has been a project, a starter, a backup, a Super Bowl champion and soldiered through some mediocre seasons.

The Arizona Cardinals are designating running back Trey Benson to return from injured reserve, but Marvin Harrison Jr. is out against the Jaguars.

The Jacksonville Jaguars opened their practice week on Wednesday in preparation for Sunday’s game against the Arizona Cardinals and released their first injury report of the week. The Jaguars listed 16 players on their report, with two not practicing and the remainder limited. Ten are starters.

Find single game tickets to the Jacksonville Jaguars vs. Arizona Cardinals NFL Week 12 matchup on Sunday, November 23, 2025 at State Farm Stadium.

On Sunday at 1 p.m. ET at M&T Bank Stadium, Lamar Jackson and the Baltimore Ravens match up with the New York Jets in Week 12. Jackson completed 14-of-25 passes (56.0%) for 193 yards, no passing touchdowns,