The San Francisco 49ers have beaten the Indianapolis Colts 48-27 on “Monday Night Football” behind Brock Purdy ’s career-high five touchdown passes. Christian McCaffrey racked up 146 total scrimmage ...

San Francisco 49ers linebacker Dee Winters made a huge play in the fourth quarter to finish off the Indianapolis Colts.

Now back as the wily super-veteran, Rivers is pulling out all the tricks. And on this one, it worked to give the Colts an ...

Another win stacked up by the San Francisco 49ers. Their offense lit up the Indianapolis Colts in primetime to get the win ...

The tightrope finally snapped inside Lucas Oil Stadium on primetime Monday Night Football as the Indianapolis Colts suffered ...

Brock Purdy was a vastly different quarterback on Monday night against the Colts compared to his prior Monday Night Football ...

Christian McCaffrey accomplished a milestone he hasn't pulled off since 2023 during the 49ers' matchup against the Colts on ...

The Jacksonville Jaguars will have a chance at winning the Super Bowl this season after earning a playoff spot following ...

San Francisco 49ers running back Christian McCaffery catches a 9-yard touchdown pass from quarterback Brock Purdy.

While the 49ers have won a fifth consecutive game, the Colts have now lost five straight. Here's the winners and losers from "Monday Night Football." ...

Brock Purdy throws a career-high five touchdown passes and Dee Winters returns an interception 74 yards for a TD in a 48-27 ...

Brock Purdy lanzó un máximo de carrera de cinco pases de touchdown y Dee Winters devolvió 74 yardas una intercepción en el último pase de Philip Rivers para anotar, liderando la victoria del lunes de ...