In 2021, Trey Lance went third overall to the 49ers, and Mac Jones followed 12 picks later to the Patriots.

Colin Cowherd says the 49ers should "cut bait" with Brandon Aiyuk now because of all the drama he's causing.

Gracen Halton shores up the 49ers defensive front heading into the 2026 season.

San Francisco 49ers quarterback Mac Jones dropped a hilarious comparison about Seattle Seahawks star Sam Darnold's career after the 2023 NFL season.

The Tennessee Titans' preseason matchups against the 49ers and Bears will each air on NFL Network.

San Francisco 49ers wide receiver Brandon Aiyuk is continuing to voice his frustrations on social media as he tries to force ...

Christian McCaffrey put up historic numbers in 2025, but new warning signs have 49ers fans concerned heading into the 2026 ...

Mac Jones wants to shut down any notion of a quarterback controversy with the San Francisco 49ers. Jones made it clear the ...

NFL Network Chief National Reporter Steve Wyche provides insight into the San Francisco 49ers revamped defense ahead of the ...

The 49ers wide receiver is seeking to exit the San Francisco organization, and his social media activity details all the jabs ...

Seven San Francisco 49ers found spots on ESPN's newly unveiled "Domestic Cup of American Football," an exercise from analyst ...

Below are some stories from the last week about the 49ers for Cardinals fans to know. The 49ers acquired defensive lineman ...