The Indianapolis Colts host the San Francisco 49ers in NFL Week 16 action on 'Monday Night Football': Live score updates, ...

The Indianapolis Colts have lost starting center Tanor Bortolini for the rest of the game against the San Francisco 49ers in ...

Pro Bowl defensive tackle DeForest Buckner was activated off injured reserve and will play Monday night when the Indianapolis ...

The San Francisco 49ers visit the Indianapolis Colts in Week 16 of the NFL season. Follow along for highlights and live score ...

This week’s Monday Night Football features the San Francisco 49ers visiting the Indianapolis Colts. The 49ers are 10-4, but ...

One San Francisco 49ers rookie could be in line for his NFL debut when the 49ers visit the Indianapolis Colts on Monday.

The San Francisco 49ers still have a chance to claim the one seed in the NFC playoff bracket with a win in Week 16 over the ...

Indianapolis Colts running back Ameer Abdullah fumbles the ball on the kick return for a San Francisco 49ers fumble recovery.

The Colts' playoff chances have taken a nosedive along with their record of late: they're on a four-game losing streak after ...

San Francisco aims to improve playoff position while Indianapolis fights for postseason hopes with Philip Rivers at ...

The Indianapolis Colts are getting huge defensive help just in time for a clash with the San Francisco 49ers tonight.

Philip Rivers is back at quarterback. IndyStar's Joel A. Erickson answers your questions about Colts vs 49ers on Monday Night ...