Brock Purdy stats: 49ers QB makes MNF history with career game vs. Colts originally appeared on The Sporting News. Add The ...

The Colts' loss clinched playoff spots for the Bills and Chargers. The 49ers had already clinched their spot in the NFC, and ...

The San Francisco 49ers have beaten the Indianapolis Colts 48-27 on “Monday Night Football” behind Brock Purdy ’s career-high five touchdown passes. Christian McCaffrey racked up 146 total scrimmage ...

Brock Purdy was a vastly different quarterback on Monday night against the Colts compared to his prior Monday Night Football ...

Another win stacked up by the San Francisco 49ers. Their offense lit up the Indianapolis Colts in primetime to get the win ...

In the middle of a quarterback shootout, the 49ers saw another one of their key offensive pass-catching options go down.

TD MNF night lifts the 49ers past the Colts and sets a clear path to the NFL Playoffs No. 1 seed with two home wins.

His game plan was far too simple. Colts quarterback Philip Rivers threw nothing but duck balls all night, but he was able to ...

Christian McCaffrey accomplished a milestone he hasn't pulled off since 2023 during the 49ers' matchup against the Colts on ...

Watch the best plays from San Francisco 49ers quarterback Brock Purdy's 5-touchdown game vs. the Indianapolis Colts in Week ...

Who is in the NFL playoffs? Seven teams have now clinched berths in field with Patriots, 49ers, Eagles, Bears, Seahawks clinching berths in Week 16.

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats and more for Colts-49ers.