Triglia discusses her research at the intersection of genetics, epigenetics, single-cell genomics and computational biology.

Using CRISPR, researchers have modelled the different developmental stages of childhood leukaemia. They discovered that ...

Analysis of proteins is not simple. Unlike DNA, there is incredible diversity in the concentration and variety of proteins created by a cell at any given moment. In our Proteomics Playbook we outline ...

As advancements in genetic technologies accelerate at an astonishing pace, the potential for gene editing to transform our world becomes closer to being realised. With the advent of revolutionary ...

Illumina’s systems employ short-read sequencing techniques, which has been the predominant NGS technology for the last decade. The company has made huge advances in the NGS space and now markets a ...

The idea that the experiences of our ancestors shape who we are today is not a novel one. In fact, throughout history, great thinkers from around the world have proposed theories and ideas to explain ...

Single-cell transcriptomics, or scRNA-seq, is widely used for analysing the transcriptome of single-cell populations. With scRNA-seq, gene expression profiling can explore genotype-phenotype ...

Two things that have defined the 21 st century are genomics and the internet. Through a combination of these has emerged a controversial type of ‘influencer’ on the internet – self-gene-editors or ...

Written by Arpita Kulkarni (Director of the Functional Genomics and Bioinformatics Core at HMS/BIDMC). Across the life sciences, a quiet anxiety is growing: what is the role of the experimental ...

Nucleic acid sequencing has become an integral part of modern biomedical research. The advances in sequencing technology, from its invention to modern-day equivalents, have been extraordinary. 2022 ...

How will multi-omics change healthcare? With new ways to integrate data, new applications in precision medicine, and the emerging potential of AI and machine learning for analysis, it is an exciting ...

Since the discovery of the basic double-helix structure of DNA In the 1950’s, scientists have devoted a huge amount of effort to determine the sequence of a variety of different genomics. It took over ...