In Alzheimer's, brain cells die too soon. In cancer, dangerous cells don't die soon enough. That's because both diseases alter the way cells decide when to end their lives, a process called programmed ...
Randal Halfmann at the Stowers Institute for Medical Research in Kansas City is hoping to treat diseases including cancer and Alzheimer's by influencing how cells make life-or-death decisions. In ...
In five years since AlphaFold's debut, it has transformed basic biochemical research. But its long-term effect on drug discovery remains unclear.
WEST LAFAYETTE, Ind. — The shared culprit in a slew of diseases — cancers, neurodegenerative diseases, diabetes — is molecules our cells have made incorrectly. Think of them as proteins gone wrong.
Repeat proteins, defined by sequential arrays of short structural motifs, offer an intriguing departure from the folding behaviour of conventional globular proteins. Their modular architecture enables ...
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