A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and other ...
This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...
Cell function is determined by how DNA is expressed into proteins. That process includes two main steps—transcription, when ...
D&D‑seq uses base editing to record DNA–protein interactions in single cells, enabling multiomics mapping of transcription ...
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The newly found genetic clock orchestrates whole bursts of gene activity at fixed moments in development, a timer scientists had long suspected but never pinned d…
A developmental timer that fires thousands of genes in precise, phase-locked bursts has been mapped in detail for the first ...
Living cells are fundamentally nonequilibrium systems, meaning they constantly spend energy through seemingly one-way, irreversible processes, such as transcribing DNA into RNA, to keep life going.
Transcription-coupled DNA damage repair represents a specialised branch of nucleotide excision repair that ensures rapid removal of lesions from the transcribed strand of active genes. When RNA ...
Transcription dynamics in the context of DNA damage response encompass the interactions between RNA polymerases and lesions within the DNA template, the resulting impact on transcriptional continuity, ...
The human heart must constantly adapt to changing demands—a task that requires tightly coordinated molecular shuffling in ...
Mobile DNA, once treated largely as genomic clutter, may help plants build new ways to respond to environmental stress.
Researchers at the University of Stuttgart have created a synthetic cell-like structure that can control the movement of ...
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