For those outside the chemistry cognoscenti, the announcement might have seemed little more than researchers patting each other on the back. But the question of protein folding had plagued scientists ...

Edited by: James Kling K.A. Dill, S. Bromberg, K.Z. Yue, K.M. Fiebig, D.P. Yee, P.D. Thomas, H.S. Chan, "Principles of protein-folding-a perspective from simple exact ...

WEST LAFAYETTE, Ind. — The shared culprit in a slew of diseases — cancers, neurodegenerative diseases, diabetes — is molecules our cells have made incorrectly. Think of them as proteins gone wrong.

High-resolution structures of nascent polypeptide chains in complex with the ribosome — the cell’s protein-synthesis machinery — reveal how the ribosome guides protein folding. Ribosomal attachment ...

Scientists discovered a role played by ribosomes during the folding of new proteins in cells. Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in ...

Protein folding raises some of biology's greatest theoretical challenges. It also lies at the root of many diseases. For example, the fundamental question of whether a protein's final tertiary ...

"The protein must backtrack in the folding process to correct the mistake, which takes time and is energetically expensive. The demonstration of this mechanism helps expand our understanding of how ...

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in their paper in Nature. Ribosomes, the cell's dedicated molecular machines ...