Alzheimer disease (AD) is the most common type of dementia, characterized by progressive neurodegeneration 1,2. Pathologically, AD is associated with the accumulation of amyloid-beta (Aβ) plaques and ...

A new study in Science Signaling identifies a previously overlooked control point in receptor tyrosine kinase (RTK) signaling, one that operates not at the plasma membrane, but at the Golgi. The ...

Through surface receptors, mammalian cells constantly perceive informational flow from the extracellular milieu. The information from the receptors is transmitted through cellular signalling cascades, ...

Signal transduction The cellular process that converts a signal, such as a hormone, growth factor, neurotransmitter, cytokine, mechanical force, or environmental cue, into biochemical changes inside ...