Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

Study reveals how two proteins cooperate in a key early step of antiviral detection, as reported by researchers at Science ...

Sometimes, transporting electrons from one cell to another is a team effort. In electroactive bacteria, that team is a group ...

Researchers have investigated the role of a certain enzyme in regulating energy in muscle and exercise performance for ...

A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...

Cornell researchers have uncovered a built-in molecular "gate" that controls the production of the molecule nitric oxide, a crucial signaling molecule throughout biology that in humans helps regulate ...

Proteins long known to be essential for hearing have been hiding a talent: they also act as gatekeepers that shuffle fatty molecules across cell membranes. When this newly discovered function goes ...

CCN5 reduced cardiac cellular senescence in preclinical models of cardiovascular disease. Learn how this could shape ...

Researchers have been studying tens of thousands of proteins and even more variations without a yardstick to compare their ...

Scientists have identified a conserved aging-related protein, EPS8, that promotes toxic protein aggregation linked to neurodegenerative diseases.