Northwestern Medicine scientists have developed a novel synthetic biomolecular condensate that can degrade intracellular ...

A hallmark of Parkinson’s disease is the buildup of Lewy bodies — misfolded clumps of the protein known as alpha-synuclein. Long before Lewy bodies form, alpha-synuclein can interfere with neurons’ ...

In simple terms: a mutation is a stable change in genetic sequence that can be copied when cells or viruses replicate. Most mutations have no detectable effect, some contribute to disease, and a small ...

Scientists at the Baylor College of Medicine say they have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called ...

For decades, pancreatic cancer has been one of the most lethal cancers, with few effective treatment options. A new drug, daraxonrasib, targets the KRAS mutation that fuels most pancreatic ...

A research team led by Purdue University's W. Andy Tao has discovered a new type of protein modification related to cellular mutation that impairs a crucial enzyme's ability to help drive energy ...

As we age, our cells acquire cancer-causing mutations, but mutations alone are rarely enough to start a tumor. An ...

A study in the journal Pharmaceuticals has uncovered how specific genetic mutations in α 2 δ-1 and α 2 δ-3 proteins linked to autism spectrum disorders (ASD) alter neuronal functionality. These ...

Specifically, they created a mouse brain map that tracked lipofuscin as the mice aged and their brains’ abilities to recycle ...