Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into ...

In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals.

Bone growth occurs through the proliferation of specialized cells of the cartilage tissue, known as chondrocytes, on either end of a bone. This process requires the synthesis of extracellular matrix ...

Growth plates are areas of cartilage found at the ends of long bones. They play a role in the bone growth of children and teens. An injury to a growth plate can affect the development of a bone. While ...

HO or abnormal bone formation in soft tissues can restrict movement and cause long-term discomfort after surgery or injury. In a new study, researchers have identified two key proteins that help ...

A bone-like composite developed at EPFL uses naturally occurring enzymes to accelerate mineralization through an energy-efficient, room-temperature process. The strong, lightweight material shows ...

Osteopenia causes reduced bone density without symptoms, driven by aging, hormones, and lifestyle factors. Early detection ...

One of the best-documented pathophysiological changes associated with microgravity and the spaceflight environment is bone loss. The reduction in bone mass and its effect following reentry could ...