In addition to brain imaging, laboratory analysis of cerebrospinal fluid is important for the diagnosis of multiple sclerosis (MS). In this study, proteomic analysis of this fluid has revealed a set ...
Impact of Broadening Trial Eligibility Criteria on the Inclusion of Patients With Brain Metastases in Cancer Clinical Trials: Time Series Analyses for 2012-2022 Effective diagnosis, prognostication, ...
May aid in the diagnosis of prion disease. RT-QuIC identifies the disease-causing agent. Total TAU and 14-3-3γ are indirect markers of neurodegenerative diseases. Assumes that the patient has a ...
Exploring the genetic blueprint of cerebrospinal fluid proteins, this study uncovers new markers and therapeutic targets that may unlock advancements in Alzheimer’s diagnosis and care. Study: ...
Twenty-two patients were included (77% female; median age 60 years). Sixty-four percent had sensitizing EGFR mutations, and 32% had an atypical EGFR mutation. Thirteen of the 22 patients (59%) were ...
CSF-ctDNA was detected in 59% of cases and showed high concordance (84%) with tumor mutations. Lower variant allelic frequency in CSF-ctDNA was associated with significantly worse survival outcomes.
Researchers have identified a set of 22 proteins that distinguish multiple sclerosis from other inflammatory diseases.
Researchers from the MPI of Biochemistry and the Technical University of Munich have discovered new diagnostic markers for multiple sclerosis (MS), a disease that affects 3 million people worldwide.
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