Introduction Onchocerciasis, commonly known as river blindness, is a parasitic disease caused by Onchocerca volvulus affecting millions predominantly in sub-Saharan Africa. Robust epidemiological ...

Fatty liver diseases (FLD) have become a significant health concern worldwide, affecting millions. The two most common types of FLD are non-alcoholic fatty liver disease (NAFLD) and ...

The pathogenesis of polycystic ovary syndrome (PCOS) is not precisely known. There are several mechanisms that have been suggested to play a role in the pathogenesis of PCOS, including hormonal ...

Despite the long history of psoriasis and psoriatic arthritis (PsA), until recently, little had been known of their underlying genetics and pathogenesis. Without this knowledge, rational clinical ...

Viral infections remain a significant global health challenge, as exemplified by recent pandemics. The complexity of virus-host interplay poses major ...

The etiopathogenesis of ankylosing spondylitis (AS) is not fully understood. However, there is strong evidence indicating that genetic factors play a pivotal role in disease susceptibility, and that ...

Identification and Validation of Novel Therapeutic Targets for Multiple Myeloma Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous clinicopathologic entity accounting for 30% of non-Hodgkin's ...

The study of metabolism within the tumour microenvironment (TME) is a rapidly evolving field that holds significant ...

Disease-related injury in any organ triggers a complex cascade of cellular and molecular responses that culminates in tissue fibrosis. Although this fibrogenic response may have adaptive features in ...