Sam Farmer makes his picks and score predictions for Week 16 of the NFL season, with the Rams sweeping the Seahawks and the Broncos extending their winning streak.

There are just three regular season weeks left in the 2025 NFL season, which means there are only three major Sunday slates to bet on some touchdowns! Playoff s

All odds referenced are courtesy of BetMGM as of publish time.

A look at who is predicted to lead the NFL in receptions in Week 16, plus accompanying player prop betting odds.

2. New England Patriots (11-3), AFC East leaders: Their 10-game heater snapped, they failed to clinch the division Sunday and lost valuable ground in their bid for the No.1 seed. But the Pats are still in driver's seat to win AFC East and can wrap up a playoff spot with a win at Baltimore. Remaining schedule: at Ravens, at Jets, vs. Dolphins.

An all-encompassing look at the matchups to exploit or avoid and lineup locks in fantasy, as well as projected scores for all NFL games.

The Bills are 10.5-point favorites in the latest Bills vs. Browns odds at DraftKings, and the over/under for total points scored is 41.5. Before you make any Browns vs. Bills picks of your own, make sure to look at the top NFL picks from the SportsLine Projection Model,

Jacksonville Jaguars quarterback Trevor Lawrence (16) scores a touchdown on a keeper during the first quarter of an NFL football matchup at EverBank Stadium, Sunday, Dec. 14, 2025, in Jacksonville, Fla.

The Philadelphia Eagles (9-5) will play NFC East rivals, the Washington Commanders (4-10), on Saturday, December 20, 2025, at Northwest Stadium. The Eagles are road favorites in this one, with the spread sitting at 7 points. The over/under in the outing is set at 44.5 points.