With that latest touchdown from San Francisco, the Colts have now conceded more points (41) tonight than they have allowed in any game all season. The 49ers have piled up 433 yards of offense so far. That ranks as only Indy's fourth-worst performance of the year.

The idea of trading up to No. 1 overall for a quarterback seems like it would be a common occurrence, but it has not happened since the Rams moved up for California's Jared Goff. Ironically, Mendoza began his collegiate career at California and Moore was not much farther away at UCLA.

A pair of Offensive Player of the Year candidates face off on Monday Night Football in Week 16, as Christian McCaffrey and the San Francisco 49ers hit the road

George Kittle draws a great matchup against a Colts defense that entered NFLWeek 16 having allowed the fifth-most receptions and yards to tight ends.

Indianapolis Colts quarterback Philip Rivers made NFL fans smile on Monday night with a great showing in the first half against the San Francisco 49ers.

It’s not really hard — that’s pass interference,” NBC rules analyst and former official Terry McAulay said during the Ravens-Patriots game.

Daily Fantasy multimillionaire Mike McClure reveals his daily Fantasy football picks for Baltimore vs. New England on 'SNF'

Texas football corner Malik Muhammad will enter the 2026 NFL Draft, he announced via Instagram on Monday.

And so the league has suspended Metcalf for two games without pay. Per the NFL, the punishment is for “conduct detrimental to the NFL for initiating a physical confrontation with a fan during Sunday’s game against the Detroit Lions.”

SportsLine's model reveals its Week 16 Fantasy football projections, PPR rankings, start-sit advice for sites like CBS Sports, ESPN and Yahoo