Scientists at the Immunology Frontier Research Center (IFReC) at Osaka University, Japan, report a new group of monocytes they call SatM. Studies in mice show that SatM may be responsible for causing ...

Atherosclerosis is driven by a complex interplay between circulating monocytes and the vascular endothelium. Endothelial cells lining the arterial wall respond to risk factors such as hyperlipidaemia, ...

In recent decades, immunotherapy has transformed cancer treatment, offering effective options for diseases once considered uncurable, such as melanoma, lung, and bladder cancers. What began as ...

Monocytes, a special type of white blood cell, secrete cytokines as inflammatory messengers that are crucial for an appropriate immune response. Researchers at the University Hospital Bonn (UKB) and ...

Combining a serum-free medium with a xeno-free serum replacement creates a reliable system for generating functional dendritic cells and macrophages. Myeloid cells such as dendritic cells and ...

A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health found that an ...

Diffuse Alveolar Damage (DAD), a severe pathological consequence of acute lung injury triggered by factors like infection or toxins, features intense inflammatory cell infiltration and carries a high ...

Rheumatoid arthritis (RA) is an autoimmune disease that causes joint inflammation and destruction. 1 There is currently no cure – and although there are many treatments, their effectiveness varies ...

Monocytes are central to innate and adaptive immunity, regulating tissue homeostasis and inflammation. However, data on their steady-state biodistribution in healthy humans are limited. We developed a ...