As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates a regenerating liver, offering new hope for future treatments. The ...

The effectiveness of non-clinical drug safety predictions is enhanced by the adoption of three-dimensional (3D) cellular models. 3D bioprinting enables the generation of complex models with spatial ...

Periportal assembloid, with the three component cell types visualized: cholangiocytes in pink, portal fibroblasts in green, and hepatocyte nuclei in blue; all cell borders are visualized in white. New ...

Assessing the toxicity of food contaminants—including carcinogenic potential—is a major challenge in evaluating the risks associated with exposure. In recent years, as part of efforts to reduce animal ...

Using human induced pluripotent stem cells, researchers have built a miniature 3D liver model that replicates the critical interaction between hepatocytes and stellate cells. As chronic liver disease ...