Cohost Jamie Lynn Sigler's husband filled in on the April 21 episode of the actresses' "MeSsy." ...

This follows a March 31 announcement from Applegate's MeSsy podcast co-host, Jamie-Lynn Sigler, that the show would go on a ...

Jamie-Lynn Sigler, who lives with multiple sclerosis, co-starred in an episode of Grey's Anatomy as a doctor with MS Sigler, 44, says that the role was created specifically for her — and for the first ...

The 54-year-old actress was reportedly admitted to a Los Angeles hospital in March, although the reason has yet to be ...

"The Sopranos" actress discusses her diagnosis, symptoms and advocacy while living in Austin with her family ...

Jamie-Lynn Sigler is joining the Grey's Anatomy cast! The actress, 44, revealed to Deadline that she'll be joining the long-running medical drama for the show's upcoming 22nd season. In a joint post ...

Jamie-Lynn Sigler teared up remembering hiding her MS for years while now playing a character with the disease on “Grey’s Anatomy.” While talking to ABC News’ Kelley Carter on “Good Morning America,” ...

Jamie-Lynn Sigler says her first role playing a character living openly with multiple sclerosis felt "divinely orchestrated." Sigler, who was diagnosed with MS more than two decades ago, guest starred ...

Former "Sopranos" star Jamie-Lynn Sigler, a Jericho native who in 2016 revealed she had been battling MS for 15 years, will play a doctor with that disease in the Jan. 15 episode of ABC’s long-running ...