Mammalian fatty acid synthase is one of the most complex molecular synthetic machines in human cells. It is also a promising target for the development of anti-cancer and anti-obesity drugs and the ...
The crystal structures of two chain-building megasynthases, the fatty acid synthases of mammals and fungi, have recently been reported. Although both are composed of modules derived from the discrete ...
Spectacular images of a molecule that shuttles omega-3 fatty acids into the brain may open a doorway for delivering neurological therapeutics to the brain. We've managed to obtain a three-dimensional ...