We demonstrate that rigid anchoring of fluorescent proteins through double tagging (FPs) in living cells can significantly enhance the contrast in fluorescence polarization microscopy (FPM) by locking ...

Stretching protein samples in all directions pulls molecules farther apart, allowing them to be visualized using only light ...

Cryo-electron microscopy (cryo-EM) can help scientists determine the three-dimensional structure of proteins in unprecedented detail. Jacques Dubochet, former group leader at EMBL, shared the 2017 ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

Bacteriophages, or phages, viruses that selectively target and infect bacteria, have drawn growing attention for their potential use in a host of biotechnological processes to benefit humankind, from ...

ST. LOUIS, MO, August 20, 2025 - A team of expert scientists led by Kirk Czymmek, PhD, director of the Advanced Bioimaging Laboratory at the Donald Danforth Plant Science Center and Heather E.

Tunable Bessel beam two-photon fluorescence microscopy enables high-speed volumetric intravital imaging of subcellular dynamics within living mouse brains with fully tunable spatial resolution and ...

In recent years, fluorescence quenching microscopy (FQM) 1-3 has emerged as a viable technique that allows for the swift, cost-effective, and accurate imaging of two-dimensional (2D) materials like ...

Microscopy is an imaging technique that enables us to see a world that would otherwise be invisible to us. Once upon a time, visualizing cells, microbes and other entities not perceptible to the naked ...

Deblurring by pixel reassignment remaps raw fluorescent microscopy images to sharpen images via pixel reassignment. Credit: Zhao and Mertz, doi 10.1117/1.AP.5.6.066004. Obtaining high-resolution ...

Explore strategies for configuring multi-color fluorescence imaging systems to enhance imaging speed and experimental ...

The brain is the most energy-demanding organ in the body, in part due to its complexity. Its components are varied and intricate: comprising different cell types, including neurons designed to ...