In eukaryotes, the leading strand DNA is synthesized by Polε and the lagging strand by Polδ. These replicative polymerases have higher processivity when paired with the DNA clamp PCNA. While the ...
XPD/Rad3-like helicases are critical enzymes for preserving genomic integrity across various organisms 1,2,3,4,5. These superfamily 2 helicases translocate 5ˈ to 3ˈ along ssDNA and unwind DNA/DNA and ...
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