The supply chain starts with raw materials and ends up with the finished products that get delivered to your store and in the hands of the consumer. Products make numerous stops along the supply chain ...
Ubiquitin (Ub) chains regulate many cellular processes, but several chain types including Lys6 linkages have remained unstudied. Here we analyze the bacterial effector E3 ligase NleL (non-Lee–encoded ...
SUMO chains act as stress-induced degradation tags or repair factor–recruiting signals at DNA lesions. Although E1 activating, E2 conjugating and E3 ligating enzymes efficiently assemble SUMO chains, ...
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