A recent article in Small highlights a new method for studying tumor cell interactions and testing anti-metastatic drugs through the development of an Under-oil Open Microfluidic System (UOMS). This ...

Researchers from Japan present a three-dimensional segregated co-culture system with a membrane insert based on silica nonwoven fabric for growing cells and observing their interactions over extended ...

An updated method for directly observing physical interactions between cells, could allow scientists to one day map every possible cell interaction. One of the fundamental goals of basic biology is ...

A Japanese research team has discovered a novel global cooperative phenomena of cell interactions in cervical cancer cells. Their findings suggest that the cells are metabolically connected in a ...

CAFs in TME: key Immunosuppressors. Secreting CXCLs, ILs, TGF-β, CCL12, PGE2, CAFs promote pro-cancer macrophage conversion, inactivate NK cells, and hinder CD8+T cell aggregation. Immune cells like ...

Scientists have engineered a lab-on-a-chip system capable of applying precisely controlled mechanical forces to biological materials that mimic the extracellular matrix.

Researchers have shown that activation of the protein YAP, known to help cancer cells survive treatment, behaves very differently in cell culture models depending on how they are grown in the lab, ...

Extracellular matrix (ECM) is the inanimate material between and around cells. It provides cells with anchorage, and influences every aspect of their behavior and fate. It is the structural framework ...