Different types of cell division failure shape whether duplicated cells survive, remain stable, or lead to cancer.

A new study led by NYU Langone Health researchers found that cancer cells are better able to resist treatments when they have ...

DNA does not float freely in the cell. Instead, it is wrapped around histone proteins to form structures called nucleosomes.

New resistance mechanism: Aneuploid cancer cells have 50–60% less PARP1, helping them survive treatment-induced oxidative stress. How it works: Chromosome errors trigger lysosomal stress, activating ...

A subtle failure during cell division can set off dramatically different outcomes, according to new research exploring whole genome duplication. A new study finds that the way a cell fails to divide ...

As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...

Cell division is one of the most fundamental and complex processes underpinning life. In human cells, thousands of molecules ...

Accurate chromosome segregation and cell division are central to maintaining genomic integrity and ensuring proper development and tissue homeostasis. These processes rely on a complex network of ...

Cell division during the early stage of embryo development is a trade-off between speed and accuracy; the cells need to ...

Structure of Ndc80 complex bound to microtubule. Ndc80 complex is the major microtubule3binding module at the kinetochore. Green: α-tubulin, light-blue:β-tubulin, dark blue: HEC1 (a4subunit of the ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...

For a living cell to divide successfully, each daughter cell must inherit the correct genetic material. In eukaryotes, segregation of duplicated chromosomes is performed by the mitotic spindle, a ...