The outer regions of the brain, the cortex, have specific layers of different cells—neurons—that are similarly ordered among all mammals, from tiny mouse brains to huge elephant brains. However, the ...
Researchers in Japan built a miniature human brain circuit using fused stem-cell–derived organoids, allowing them to watch the thalamus and cortex interact in real time. They found that the thalamus ...
The distinct aging rates of neural progenitor cells and Wnt signaling dictate mammalian cortical layer proportions.