Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Make no mistake, addiction is a neurological brain disorder. When the subject of addiction comes up, people often lean on familiar explanations. “They just need more willpower.” “Why can’t they stop ...

Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

The roots of addiction risk may lie in how young brains function long before substance use begins, according to a new study from Weill Cornell Medicine. The investigators found that children with a ...

Researchers identify the anterior insula as the brain region responsible for biasing decisions toward alcohol over social rewards in addiction.

Within the brain, chemical neurotransmitters like dopamine and norepinephrine regulate mood, emotions and many physiological and behavioral processes. Their imbalance can contribute to anxiety, ...

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as ...

Cocaine addiction may affect how the body processes iron, leading to a build-up of the mineral in the brain, according to new research from the University of Cambridge. The study, published today in ...

This post is in response to Does Binge Drinking Make Someone an Alcoholic? By Lantie Elisabeth Jorandby M.D. Most people who drink alcohol do so socially and in moderation. But for some, alcohol ...