Over the past few decades, biomedical researchers and neuroscientists have devised increasingly advanced techniques to study and alter neurophysiological processes. These include CRISPR (Clustered ...

Revvity's Dharmacon All-in-one lentiviral platform has expanded to include whole-genome library options for CRISPR knockout (CRISPRko), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa).

Fred Hutch researchers invent a CRISPR screening method to understand RNA-binding proteins often mutated in cancer and other diseases In biology’s standard tale of two acids — deoxyribonucleic (DNA) ...

This article and associated images are based on a poster originally authored by Ulrike Künzel, Chun Hao Wong, Erica Bello, Antigoni Gogolou, Shaun Maguire, Ben Pearson, Davide Gianni, Coralie Viollet, ...

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens, a large number of cells are edited ...

Fighting off pathogens is a tour de force that must happen with speed and precision. A team of researchers at CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, and at ...

New research has found a novel target with therapeutic potential for metastatic eye melanoma—an aggressive eye cancer—with implications for a range of other cancers. Subscribe to our newsletter for ...

DNA is transcribed into RNA, which is then translated into proteins. This is the central dogma of molecular biology – a mantra taught to every biology undergraduate student to be recalled and expanded ...

More than 10 million people develop tuberculosis (TB) each year, yet about 40% go undiagnosed. The main culprit is reliance on sputum-based testing, which many patients—particularly those who are ...